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BMI1, Human (His)

HY-P701224
MedChem Express
Protein IDP35226
Product group Proteins / Signaling Molecules
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Overview

  • Supplier
    MedChem Express
  • Product Name
    BMI1, Human (His)
  • Delivery Days Customer
    14
  • Certification
    Research Use Only
  • Estimated Purity
    90.00
  • Gene ID648
  • Target name
    BMI1
  • Target description
    BMI1 proto-oncogene, polycomb ring finger
  • Target synonyms
    B lymphoma Mo-MLV insertion region 1 homolog; BMI1 polycomb ring finger oncogene; BMI1 polycomb ring finger proto-oncogene; FLVI2/BMI1; flvi-2/bmi-1; murine leukemia viral (bmi-1) oncogene homolog; PCGF4; polycomb complex protein BMI-1; polycomb group protein Bmi1; polycomb group RING finger protein 4; ring finger protein 51; RNF51
  • Protein IDP35226
  • Protein Name
    Polycomb complex protein BMI-1
  • Scientific Description
    BMI1 Protein, a component of the Polycomb group PRC1-like complex, maintains transcriptional repression in genes, including Hox genes, by monoubiquitinating histone H2A. It regulates the E3 ubiquitin-protein ligase activity of RNF2/RING2. Interacts with various partners in the PRC1-like complex, such as RNF2, CBX2, CBX4, CBX8, PHC1, PHC2, PHC3, and UB2D3, forming complexes crucial for chromatin modification and gene expression control. BMI1 Protein, Human (E.coli,N-His) is the recombinant human-derived BMI1 protein, expressed by E. coli , with N-6*His labeled tag.
  • Storage Instruction
    -20°C
  • UNSPSC
    41116100

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