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BMP-3, Human

HY-P79077
MedChem Express
Protein IDP12645
Product group Proteins / Signaling Molecules
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Overview

  • Supplier
    MedChem Express
  • Product Name
    BMP-3, Human
  • Delivery Days Customer
    5
  • Certification
    Research Use Only
  • Estimated Purity
    98.00
  • Gene ID651
  • Target name
    BMP3
  • Target description
    bone morphogenetic protein 3
  • Target synonyms
    BMP-3A; bone morphogenetic protein 3; bone morphogenetic protein 3 (osteogenic); bone morphogenetic protein 3A; osteogenin
  • Protein IDP12645
  • Protein Name
    Bone morphogenetic protein 3
  • Scientific Description
    BMP-3 Protein, a TGF-beta superfamily member, crucially influences early skeletal formation and acts as a bone density negative regulator. It counteracts osteogenic BMPs, hindering osteoprogenitor differentiation. BMP-3 initiates signaling via ACVR2B, activating SMAD2-dependent and SMAD-independent pathways, including TAK1 and JNK. Structurally, it forms homodimers with disulfide bonds, interacting with ACVR2B to regulate functions. BMP-3 Protein, Human is the recombinant human-derived BMP-3 protein, expressed by E. coli , with tag free.
  • Storage Instruction
    -20°C
  • UNSPSC
    41116100

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