BMP-3, Human
HY-P79077
Protein IDP12645
Product group Proteins / Signaling Molecules
Overview
- SupplierMedChem Express
- Product NameBMP-3, Human
- Delivery Days Customer5
- CertificationResearch Use Only
- Estimated Purity98.00
- Gene ID651
- Target nameBMP3
- Target descriptionbone morphogenetic protein 3
- Target synonymsBMP-3A; bone morphogenetic protein 3; bone morphogenetic protein 3 (osteogenic); bone morphogenetic protein 3A; osteogenin
- Protein IDP12645
- Protein NameBone morphogenetic protein 3
- Scientific DescriptionBMP-3 Protein, a TGF-beta superfamily member, crucially influences early skeletal formation and acts as a bone density negative regulator. It counteracts osteogenic BMPs, hindering osteoprogenitor differentiation. BMP-3 initiates signaling via ACVR2B, activating SMAD2-dependent and SMAD-independent pathways, including TAK1 and JNK. Structurally, it forms homodimers with disulfide bonds, interacting with ACVR2B to regulate functions. BMP-3 Protein, Human is the recombinant human-derived BMP-3 protein, expressed by E. coli , with tag free.
- Storage Instruction-20°C
- UNSPSC41116100