BMP-7, Human (His)

MedChem Express

BMP-7, Human (His)

10

Research Use Only

95.0

BMP7

bone morphogenetic protein 7

bone morphogenetic protein 7; OP-1; osteogenic protein 1

Bone morphogenetic protein 7

Bone morphogenetic protein 7 (BMP-7) is a polymorphic ligand protein belonging to the TGF-beta family. BMP-7 is involved in regulating the proliferation, invasion and migration of cancer cells and is associated with a variety of human tumors[1]. BMP-7 binds ALK2 or ACVR2A/BMPR2 excitation signal, which is terminated by SMADs regulation[2]. BMP-7 is involved in the BMP-7-SMad1/5/9 signaling pathway, which is associated with the epithelial-mesenchymal transition (EMT) process[1]. BMP-7 also eliminates vascular inflammation, maintains vascular integrity[3], reduces vascular calcification, and stimulates in situ phosphate ossification deposition[4].

-20°C

41116100