BMP-7 Protein, Human

Research Use Only
MedChem Express
Protein IDP18075
Product group Proteins / Signaling Molecules
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  • Supplier
    MedChem Express
  • Product Name
    BMP-7 Protein, Human
  • Delivery Days Customer
  • Certification
    Research Use Only
  • Protein IDP18075
  • Protein Name
    Bone morphogenetic protein 7
  • Scientific Description
    Bone morphogenetic protein 7 (BMP-7) is a polymorphic ligand protein belonging to the TGFbeta family. BMP-7 is involved in regulating the proliferation, invasion and migration of cancer cells and is associated with a variety of human tumors. BMP-7 binds ALK2 or ACVR2A/BMPR2 excitation signal, which is terminated by SMADs regulation. BMP-7 is involved in the BMP-7-SMad1/5/9 signaling pathway, which is associated with the epithelial-mesenchymal transition (EMT) process. BMP-7 also eliminates vascular inflammation, maintains vascular integrity, reduces vascular calcification, and stimulates in situ phosphate ossification deposition. The total length of human BMP-7 protein is 431 amino acids (M1-H431), with 4 glycosylation domains. BMP-7 Protein, Human has a total length of 139 amino acids (S293-H431), is expressed in E. coli cells.
  • Storage Instruction
    2°C to 8°C,-20°C or -80°C