
Immunohistochemistry of paraffin-embedded human breast cancer using CSB-PA002734LA01HU at dilution of 1:100
BMP10 Antibody
CSB-PA002734LA01HU
ApplicationsELISA, ImmunoHistoChemistry
Product group Antibodies
ReactivityHuman
TargetBMP10
Overview
- SupplierCusabio
- Product NameBMP10 Antibody
- Delivery Days Customer20
- ApplicationsELISA, ImmunoHistoChemistry
- CertificationResearch Use Only
- ClonalityPolyclonal
- ConjugateUnconjugated
- Gene ID27302
- Target nameBMP10
- Target descriptionbone morphogenetic protein 10
- Target synonymsbone morphogenetic protein 10
- HostRabbit
- IsotypeIgG
- Protein IDO95393
- Protein NameBone morphogenetic protein 10
- Scientific DescriptionRequired for maintaining the proliferative activity of embryonic cardiomyocytes by preventing premature activation of the negative cell cycle regulator CDKN1C/p57KIP and maintaining the required expression levels of cardiogenic factors such as MEF2C and NKX2-5. Acts as a ligand for ACVRL1/ALK1, BMPR1A/ALK3 and BMPR1B/ALK6, leading to activation of SMAD1, SMAD5 and SMAD8 transcription factors. Inhibits endothelial cell migration and growth. May reduce cell migration and cell matrix adhesion in breast cancer cell lines.
- ReactivityHuman
- Storage Instruction-20°C or -80°C
- UNSPSC41116161