BMP8b antibody [GT1017]

GeneTex

BMP8b antibody [GT1017]

9

WB: 1:5000-1:20000. ICC/IF: 1:100-1:1000. *Optimal dilutions/concentrations should be determined by the researcher.Not tested in other applications.

ImmunoFluorescence, Western Blot, ImmunoCytoChemistry

Research Use Only

Monoclonal

GT1017

1 mg/ml

Unconjugated

BMP8B

bone morphogenetic protein 8b

BMP8; bone morphogenetic protein 8 (osteogenic protein 2); bone morphogenetic protein 8B; OP2; osteogenic protein 2

Mouse

IgG2a

Bone morphogenetic protein 8B

This gene encodes a secreted ligand of the TGF-beta (transforming growth factor-beta) superfamily of proteins. Ligands of this family bind various TGF-beta receptors leading to recruitment and activation of SMAD family transcription factors that regulate gene expression. The encoded preproprotein is proteolytically processed to generate each subunit of the disulfide-linked homodimer. The encoded protein stimulates thermogenesis in brown adipose tissue. Expression of this gene may be downregulated in pancreatic cancer. This gene may have arose from a gene duplication event and its gene duplicate is also present on chromosome 1. [provided by RefSeq, Jul 2016]

Human

-20°C or -80°C,2°C to 8°C

12352203