BMS-1 [1675201-83-8]

TargetMol Chemicals

BMS-1 [1675201-83-8]

4

1675201-83-8

Chemical

Research Use Only

BMS-1

99.86%

C29H33NO5

475.58

BMS-1 (PD-1/PD-L1 inhibitor 1) is an inhibitor of the PD1-PD-L1 protein-protein interaction. It also acts as an immunomodulator. Programmed death ligand 1 (PD-L1) is a protein in humans that is encoded by the CD274 gene and the upregulation of PD-L1 allows Ys to evade the host immune system. High tumor expression of PD-L1 was associated with increased tumor aggressiveness and a 4.5-fold increased risk of death.

3 years

COc1cc(OCc2cccc(c2C)-c2ccccc2)cc(OC)c1CN1CCCC[C@H]1C(O)=O

-20°C

12352200