BMS-1001 hydrochloride [2113650-04-5]

TargetMol Chemicals

BMS-1001 hydrochloride

4

2113650-04-5

Chemical

Research Use Only

BMS-1001 hydrochloride

0.9736

C35H35ClN2O7

631.11

BMS-1001 hydrochloride is an orally active inhibitor of human PD-1/PD-L1 immune checkpoint with low-toxicity in cells.BMS-1001 alleviates the inhibitory effect of the soluble PD-L1 on the T-cell receptor-mediated activation of T-lymphocytes. BMS-1001 is capable of alleviating the PD-1/PD-L1 immune checkpoint-mediated exhaustion of Jurkat T-lymphocytes.

3 years

Cl.Cc1cc(CN[C@H](CO)C(O)=O)c(OCc2cccc(c2)C#N)cc1OCc1cccc(c1C)-c1ccc2OCCOc2c1

-20°C

12352200