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BMS 182874 (hydrochloride)

HY-103458
MedChem Express
CAS Number1215703-04-0
Product group Chemicals
Molecular Weight381.88
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Overview

  • Supplier
    MedChem Express
  • Product Name
    BMS 182874 (hydrochloride)
  • Delivery Days Customer
    5
  • CAS Number
    1215703-04-0
  • Certification
    Research Use Only
  • Molecular Formula
    C17H20ClN3O3S
  • Molecular Weight
    381.88
  • Scientific Description
    BMS 182874 hydrochloride is an orallyactive, highly selective endothelin receptor (ETA receptor) antagonist, with IC50 value of 0.150 microM, Ki of 0.055 microM. BMS 182874 hydrochloride reduces the arterial pressure of Deoxycorticosterone acetate (HY-B1472) induced hypertension model in rats, and can be used for cardiovascular disease research[1].
  • SMILES
    O=S(C1=C2C=CC=C(C2=CC=C1)N(C)C)(NC3=C(C(C)=NO3)C)=O.Cl
  • UNSPSC
    12352200