BMS-199264 (hydrochloride) [186180-83-6]

MedChem Express

BMS-199264 (hydrochloride) [186180-83-6]

5

186180-83-6

Research Use Only

99.28

C26H32Cl2N4O4S

567.53

BMS-199264 hydrochloride is an inhibitor of F1F0 ATP hydrolase (IC50=0.5 microM) without inhibitory effect on F1F0 ATP synthase. BMS-199264 hydrochloride selectively inhibits ATP decline during ischemia to reduces cardiac necrosis. BMS-199264 hydrochloride also enhances the recovery of contractile function following reperfusion[1].

O[C@@H]1C(C)(OC2=CC=C(C=C2[C@H]1N(CC3=NC=CN3)C4=CC=C(C=C4)Cl)S(=O)(N5CCCCC5)=O)C.Cl

2°C to 8°C

12352200