BMS-243117 [225521-80-2]
HY-120622
CAS Number225521-80-2
Product group Chemicals
Molecular Weight416.92
Overview
- SupplierMedChem Express
- Product NameBMS-243117 [225521-80-2]
- Delivery Days Customer5
- CAS Number225521-80-2
- CertificationResearch Use Only
- Molecular FormulaC20H21ClN4O2S
- Molecular Weight416.92
- Scientific DescriptionBMS-243117 is a potent, and selective benzothiazole based p56Lck inhibitor with an IC50 of 4 nM. BMS-243117 inhibits anti-CD3/anti-CD28 induced PBL (human peripheral blood T-cells) proliferation with an IC50 of 1.1 microM. BMS-243117 binds in an extended conformation to the ATP-binding site of Lck[1].
- SMILESO=C(C1=CC=C2N=C(NC(NC(C)(C)C)=O)SC2=C1)NC3=C(C)C=CC=C3Cl
- UNSPSC12352200