BMS-248360 [254737-87-6]

MedChem Express

BMS-248360 [254737-87-6]

10

254737-87-6

Research Use Only

C36H45N5O5S

659.84

BMS-248360 is a potent and orally active dual antagonist of both angiotensin II receptor (AT1) and endothelin A (ETA) receptor, with Kis of 10 nM and 1.9 nM for hAT1 and hETA receptor, respectively. BMS-248360 displays hypertensive effects[1].

O=S(C1=CC=CC=C1C2=CC=C(CN3C(CCCC)=NC4(CCCC4)C3=O)C=C2CN5C(C(C)(C)CC5)=O)(NC6=C(C)C(C)=NO6)=O

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