BMS-250749 [406913-72-2]

MedChem Express

BMS-250749 [406913-72-2]

5

406913-72-2

Research Use Only

C26H18F3N3O6

525.43

BMS-250749 is a topoisomerase I (Top I) inhibitor of the fluoroglycosyl-3,9-difluoroindolecarbazole class. BMS-250749 exhibits potent cytotoxicity and selectivity, and shows curative antitumor activity against Lewis lung cancer. BMS-250749 exhibits broad-spectrum antitumor activity superior to CPT-11 in certain preclinical xenograft models.[1].

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