BMS-378806

MedChem Express

BMS-378806 [357263-13-9]

5

357263-13-9

Research Use Only

98.94

C22H22N4O4

406.43

BMS-378806 is a potent HIV-1 attachment inhibitor that interferes with CD4-gp120 interactions. BMS-378806 selectively inhibits the binding of HIV-1 gp120 to the CD4 receptor with EC 50 of 0.85-26.5 nM in virus.

COC1=C2C(NC=C2C(C(N3CCN(C[C@H]3C)C(C4=CC=CC=C4)=O)=O)=O)=NC=C1

-20°C,2°C to 8°C

12352200