BMS-536924
M1957
CAS Number468740-43-4
Product group Chemicals
Estimated Purity0.9865
Molecular Weight479.96
Overview
- SupplierAbMole BioScience
- Product NameBMS-536924
- Delivery Days Customer9
- CAS Number468740-43-4
- Category SupplierChemical
- CertificationResearch Use Only
- Estimated Purity0.9865
- Molecular FormulaC25H26ClN5O3
- Molecular Weight479.96
- Scientific DescriptionBms-536924 is an orally active, competitive and selective insulin-like growth factor receptor (IGF-1R) kinase and insulin receptor (IR) inhibitor with IC50 of 100 nM and 73 nM, respectively. It also showed moderate inhibitory activity against Mek, Fak and Lck, but almost no inhibitory activity against Akt1 and MAPK1/2.
- SMILESCC1=C2N=C([NH]C2=CC(=C1)N3CCOCC3)C4=C(NCC(O)C5=CC=CC(=C5)Cl)C=CNC4=O
- UNSPSC12352200