BMS-538305 (hydrochloride) [841302-51-0]

MedChem Express

BMS-538305 (hydrochloride) [841302-51-0]

9

841302-51-0

Research Use Only

C17H27ClN2O2

326.86

BMS-538305 hydrochloride is a potent and selective inhibitor of dipeptidyl peptidase IV (DPP-IV), exhibiting strong biological activity by forming a reversible covalent complex with the enzyme. BMS-538305 hydrochloride demonstrates its mechanism of action through the covalent attachment between the nitrile carbon of the inhibitor and the enzyme residue S630, as unveiled by the X-ray crystal structure analysis.

O=C(N1[C@@H]2[C@H](CC1)C2)[C@H]([C@@]34C[C@@](C[C@H](C[C@H]5C4)C3)(C5)O)N.Cl

12352200