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ProductsBack/BMS-8 [1675201-90-7]
CgoaEWY7TE-EYL1UAAAAALLMsY8249.png
CgoaEWY7TE-EYL1UAAAAALLMsY8249.png
CgoaEWY7TE-EYL1UAAAAALLMsY8249.png

BMS-8 [1675201-90-7]

Research Use Only
T26859
TargetMol Chemicals
CAS Number1675201-90-7
DownloadMSDS
Product group Chemicals
Molecular Weight494.42
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Overview

  • Supplier
    TargetMol Chemicals
  • Product Name
    BMS-8 [1675201-90-7]
  • Delivery Days Customer
    4
  • CAS Number
    1675201-90-7
  • Category Supplier
    Chemical
  • Certification
    Research Use Only
  • Chemical Name
    BMS-8
  • Molecular Formula
    C27H28BrNO3
  • Molecular Weight
    494.42
  • Scientific Description
    BMS-8 is a novel inhibitor of the PD-1/PD-L1 interaction (IC50: 7.2 microM) by binding directly to PD-L1 and inducing the formation of PD-L1 homodimers.
  • Shelf life instruction
    3 years
  • SMILES
    Cc1c(COc2ccc(CN3CCCCC3C(O)=O)cc2Br)cccc1-c1ccccc1
  • Storage Instruction
    -20°C
  • UNSPSC
    12352200

References

  • Gaudy-Marqueste C, Dussouil AS, Carron R, Troin L, Malissen N, Loundou A, Monestier S, Mallet S, Richard MA, Régis JM, Grob JJ. Survival of melanoma patients treated with targeted therapy and immunotherapy after systematic upfront control of brain metastases by radiosurgery. Eur J Cancer. 2017 Oct;84:44-54.
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