BMS-833923

MedChem Express

BMS-833923 [1059734-66-5]

10

1059734-66-5

Research Use Only

99.82

C30H27N5O

473.57

BMS-833923 (XL-139) is an orally biocompatible Smoothened (Smo) inhibitor with anti-tumor activity. It can inhibit the binding of BODIPY cyclopamine to SMO in a dose-dependent manner with an IC 50 of 21 nM [1] .

O=C(NC1=CC(CNC)=CC=C1C)C2=CC=C(NC3=NC(C4=CC=CC=C4)=C5C=CC=CC5=N3)C=C2

-20°C,2°C to 8°C

12352200