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BMS-986122 [313669-88-4]

Research Use Only
T26869
TargetMol Chemicals
CAS Number313669-88-4
Product group Chemicals
Molecular Weight448.78
Price on request
Packing Size
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Overview

  • Supplier
    TargetMol Chemicals
  • Product Name
    BMS-986122 [313669-88-4]
  • Delivery Days Customer
    4
  • CAS Number
    313669-88-4
  • Category Supplier
    Chemical
  • Certification
    Research Use Only
  • Chemical Name
    BMS-986122
  • Molecular Formula
    C16H15BrClNO3S2
  • Molecular Weight
    448.78
  • Scientific Description
    BMS-986122 (BMS 986122) is a positive allosteric modulator of micro-opioid receptors that increases beta-arrestin recruitment stimulated by endomorphin 1 in U2OS-OPRM1 human osteosarcoma cells expressing micro-opioid receptors (EC50 = 3 microM).
  • Shelf life instruction
    3 years
  • SMILES
    COc1ccc(cc1Br)C1SCCN1S(=O)(=O)c1ccc(Cl)cc1
  • Storage Instruction
    -20°C
  • UNSPSC
    12352200

References

  • Burford NT, et al. Discovery of positive allosteric modulators and silent allosteric modulators of the u-opioid receptor. Proc Natl Acad Sci U S A. 2013;110(26):10830-10835.
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