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ProductsBack/BMS-986169 [1801151-08-5]

BMS-986169 [1801151-08-5]

HY-119886
MedChem Express
CAS Number1801151-08-5
Product group Chemicals
Molecular Weight382.47
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Overview

  • Supplier
    MedChem Express
  • Product Name
    BMS-986169 [1801151-08-5]
  • Delivery Days Customer
    9
  • CAS Number
    1801151-08-5
  • Certification
    Research Use Only
  • Molecular Formula
    C23H27FN2O2
  • Molecular Weight
    382.47
  • Scientific Description
    BMS-986169 is an inhibitor of the glutamate N-methyl-D-aspartate 2B receptor (GluN2B). BMS-986169 has a high binding affinity for the allosteric regulatory site of the GluN2B subunit, with a Ki value of 4.03-6.3 nM. BMS-986169 can inhibit the function of GluN2B receptors in Xenopus oocytes, with an IC50 value of 24.1 nM. BMS-986169 can also inhibit the activity of the hERG channel, with an IC50 value of 28.4 microM. BMS-986169 can be used in research on treatment-resistant depression[1].
  • SMILES
    O=C1N(CC[C@H]1N2C[C@H]([C@@H](CC2)C3=CC=C(C=C3)O)F)CC4=CC=C(C=C4)C
  • UNSPSC
    12352200

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