BMS-986172 [1808258-99-2]

MedChem Express

BMS-986172 [1808258-99-2]

14

1808258-99-2

Research Use Only

99.48

C24H22F7N7O3

589.47

BMS-986172 is an orally active, highly selective MGAT2 inhibitor with an IC50 of 4.6 nM and 20 nM for hMGAT2 and mMGAT2, respectively. BMS-986172 has a T1/2>120 min in vitro assays. BMS-986172 reduces food intake and body weight. BMS-986172 has the potential for metabolic disorders such as obesity and NASH research[1].

FC1=C([C@]2(C(F)(F)F)CC(C3=NN(C=C3)CC4CC4)=C(C(N2)=O)N5N=NNC5=O)C=CC(OCCCC(F)(F)F)=C1

2°C to 8°C

12131703