BMS-986470 [3036554-12-5]

MedChem Express

BMS-986470 [3036554-12-5]

5

CHEMICAL,general_chemicals_reagents

Research Use Only

C29H25N5O5

523.54

BMS-986470, a HbF-activating CRBN E3 ligase modulator (CELMoD), is an orally active dual molecular glue degrader targeting ZBTB7A and WIZ. BMS-986470 has potent gamma-globin induction activity. BMS-986470 can be used for sickle cell disease (SCD) research[1].

CC1=NC=CC(C2=CC3=C(N(C(CC3)=O)C)C=C2NC4=CC=CC5=C4C(N(C5=O)[C@H]6CCC(NC6=O)=O)=O)=C1

-20°C, 3 years; 4°C, 2 years (Powder)

12352005