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BMSpep-57 hydrochloride

M31223
AbMole BioScience
CAS Number1629655-80-6
Product group Chemicals
Molecular Weight1904.63
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Overview

  • Supplier
    AbMole BioScience
  • Product Name
    BMSpep-57 hydrochloride
  • Delivery Days Customer
    9
  • CAS Number
    1629655-80-6
  • Category Supplier
    Chemical
  • Certification
    Research Use Only
  • Molecular Formula
    C89H127ClN24O19S
  • Molecular Weight
    1904.63
  • Scientific Description
    BMSpep-57 hydrochloride is a potent and competitive macrocyclic peptide inhibitor of PD-1/PD-L1 interaction with an IC50 of 7.68 nM. BMSpep-57 hydrochloride binds to PD-L1 with Kds of 19 nM and 19.88 nM in MST and SPR assays, respectively. BMSpep-57 hydrochloride facilitates T cell function by in creasing IL-2 production in PBMCs.
  • Storage Instruction
    Store at ≤ -20°C, dry, sealed
  • UNSPSC
    12352200

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