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ProductsBack/BMT-090605 [1551403-51-0]
CgoaEGY7PwiEHqIxAAAAAAl6OrU982.png
CgoaEGY7PwiEHqIxAAAAAAl6OrU982.png
CgoaEGY7PwiEHqIxAAAAAAl6OrU982.png

BMT-090605 [1551403-51-0]

Research Use Only
T14691
TargetMol Chemicals
CAS Number1551403-51-0
DownloadMSDS
Product group Chemicals
Molecular Weight364.44
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Overview

  • Supplier
    TargetMol Chemicals
  • Product Name
    BMT-090605 [1551403-51-0]
  • Delivery Days Customer
    86
  • CAS Number
    1551403-51-0
  • Category Supplier
    Chemical
  • Certification
    Research Use Only
  • Chemical Name
    BMT-090605
  • Molecular Formula
    C21H24N4O2
  • Molecular Weight
    364.44
  • Scientific Description
    BMT-090605 is a potent, selective AAK1 inhibitor with an IC50 of 0.6 nM, and inhibits BMP-2-inducible protein kinase (BIKE) and Cyclin G-associated kinase (GAK) with IC50s of 45 and 60 nM, respectively[1]. BMT-090605 also exhibits antinociceptive activity.
  • Shelf life instruction
    3 years
  • SMILES
    CN1C=2C(C=3C(C1=O)=C(C)N=CC3)=CC(C#N)=C(OC[C@H](CC(C)C)N)C2
  • Storage Instruction
    -20°C
  • UNSPSC
    12352200

References

  • Kostich W, et al. Inhibition of AAK1 Kinase as a Novel Therapeutic Approach to Treat Neuropathic Pain. J Pharmacol Exp Ther. 2016 Sep;358(3):371-86.
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