BO-264 [2408648-20-2]
HY-135960
CAS Number2408648-20-2
Product group Chemicals
Estimated Purity99.76
Molecular Weight353.38
Overview
- SupplierMedChem Express
- Product NameBO-264 [2408648-20-2]
- Delivery Days Customer9
- CAS Number2408648-20-2
- CertificationResearch Use Only
- Estimated Purity99.76
- Molecular FormulaC18H19N5O3
- Molecular Weight353.38
- Scientific DescriptionBO-264 is a highly potent and orally active transforming acidic coiled-coil 3 (TACC3) inhibitor with an IC50 of 188 nM and a Kd of 1.5 nM. BO-264 specifically blocks the function of FGFR3-TACC3 fusion protein. BO-264 induces spindle assembly checkpoint (SAC)-dependent mitotic arrest, DNA damage and apoptosis. BO-264 has broad-spectrum antitumor activity[1].
- SMILESCOC1=CC=C(C2=NOC(NC3=NC(N4CCOCC4)=NC=C3)=C2)C=C1
- Storage Instruction-20°C,2°C to 8°C
- UNSPSC12352200
MSDS
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Product group Chemicals
CAS Number2408648-20-2
Estimated Purity99.81%
Molecular Weight353.38
- SizePrice
Product group Chemicals
BO-264ORB1298888
CAS Number2408648-20-2
Estimated Purity99.81%
Molecular Weight353.38
- SizePrice