Boceprevir

MedChem Express

Boceprevir [394730-60-0]

10

394730-60-0

Research Use Only

99.0

C27H45N5O5

519.68

Boceprevir (EBP 520) is a potent, highly selective, orally bioavailable HCV NS3 protease inhibitor with a K i of 14 nM in both enzyme assay and an EC 90 of 350 nM in cell-based replicon assay [1] [2] [3] [4] [5] . Boceprevir inhibits SARS-CoV-2 3CL pro activity [6] .

O=C(N1[C@@H]([C@@]2([H])C(C)([C@]2(C1)[H])C)C(NC(C(C(N)=O)=O)CC3CCC3)=O)[C@@H](NC(NC(C)(C)C)=O)C(C)(C)C

-20°C

12352200