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Bohemine [189232-42-6]

HY-12843
MedChem Express
CAS Number189232-42-6
Product group Chemicals
Estimated Purity98.93
Molecular Weight340.42
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Overview

  • Supplier
    MedChem Express
  • Product Name
    Bohemine [189232-42-6]
  • Delivery Days Customer
    10
  • CAS Number
    189232-42-6
  • Certification
    Research Use Only
  • Estimated Purity
    98.93
  • Molecular Formula
    C18H24N6O
  • Molecular Weight
    340.42
  • Scientific Description
    Bohemine is a purine analogue and is a synthetic and selective CDK inhibitor with IC50s of 4.6 microM, 83 microM, and 2.7 microM for Cdk2/cyclin E, Cdk2/cyclin A, and Cdk9/cyclin T1, respectively. Bohemine also inhibits ERK2 with an IC50 of 52 microM and has less inhibitory effect on CDK1, CDK4 and CDK6. Bohemine has a broad spectrum anti-cancer activities[1][2].
  • SMILES
    OCCCNC1=NC(NCC2=CC=CC=C2)=C3N=CN(C(C)C)C3=N1
  • Storage Instruction
    -20°C
  • UNSPSC
    12352200