Bohemine

MedChem Express

Bohemine [189232-42-6]

10

189232-42-6

Research Use Only

98.93

C18H24N6O

340.42

Bohemine is a purine analogue and is a synthetic and selective CDK inhibitor with IC 50 s of 4.6 microM, 83 microM, and 2.7 microM for Cdk2/cyclin E , Cdk2/cyclin A , and Cdk9/cyclin T1 , respectively. Bohemine also inhibits ERK2 with an IC 50 of 52 microM and has less inhibitory effect on CDK1, CDK4 and CDK6. Bohemine has a broad spectrum anti-cancer activities [1] [2] .

OCCCNC1=NC(NCC2=CC=CC=C2)=C3N=CN(C(C)C)C3=N1

-20°C

12352200