Boldine

AbMole BioScience

Boldine

9

476-70-0

Chemical

C19H21NO4

327.37

Boldine is an oral effective antioxidant, anti-inflammatory, antitumor agent, and can inhibit osteoclast formation. Boldine induces apoptosis of human bladder cancer cells by regulating ERK, AKT and GSK-3bèta. Boldine ameliorates bone destruction by down-regulating the OPG/RANKL/RANK signaling pathway. It can be used in rheumatoid arthritis research.

COC1=C(O)C=C2CC3N(C)CCC4=CC(=C(OC)C(=C34)C2=C1)O

12352200