Bortezomib (Standard)

MedChem Express

Bortezomib (Standard) [179324-69-7]

5

Research Use Only

Bortezomib (Standard) is the analytical standard of Bortezomib. This product is intended for research and analytical applications. Bortezomib (PS-341) is a reversible and selective proteasome inhibitor, and potently inhibits 20S proteasome ( K i =0.6 nM) by targeting a threonine residue. Bortezomib disrupts the cell cycle, induces apoptosis, and inhibits NF-kappaB . Bortezomib is the first proteasome inhibitor anticancer agent. Anti-cancer activity [1] [2] .

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