Bosentan-d4 [1065472-77-6]

TargetMol Chemicals

Bosentan-d4 [1065472-77-6]

16

1065472-77-6

Research Use Only

Bosentan-d4

C27H25D4N5O6S

555.64

Bosentan-d4, the deuterium-labeled variant of Bosentan, serves as a competitive dual antagonist against endothelin-1 (ET) by targeting both ET A and ET B receptors. It exhibits binding affinities with K i values of 4.7 nM for ET A and 95 nM for ET B in human SMC.

3 years

[2H]C([2H])(O)C([2H])([2H])Oc1nc(nc(NS(=O)(=O)c2ccc(cc2)C(C)(C)C)c1Oc1ccccc1OC)-c1ncccn1

-20°C

12352200