Bosentan (hydrate)

MedChem Express

Bosentan (hydrate) [157212-55-0]

10

157212-55-0

Research Use Only

99.93

C27H31N5O7S

569.63

Bosentan hydrate is a competitive and dual antagonist of endothelin-1 (ET) for the ETA and ETB receptors with Ki of 4.7 nM and 95 nM in human SMC, respectively.

O=S(NC1=NC(C2=NC=CC=N2)=NC(OCCO)=C1OC3=CC=CC=C3OC)(C4=CC=C(C(C)(C)C)C=C4)=O.O

-20°C,2°C to 8°C

12352200