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Bosutinib

S1014
Selleck Chemicals
CAS Number380843-75-4
Product group Chemicals
Estimated Purity...
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Overview

  • Supplier
    Selleck Chemicals
  • Product Name
    Bosutinib (SKI-606) [380843-75-4]
  • Delivery Days Customer
    9
  • CAS Number
    380843-75-4
  • Certification
    Research Use Only
  • Estimated Purity
    ...
  • Scientific Description
    Bosutinib is a novel, dual Src/Abl inhibitor with IC50 of 1.2 nM and 1 nM in cell-free assays, respectively. Bosutinib also effectively decreases the activity of PI3K/AKT/mTOR, MAPK/ERK and JAK/STAT3 signaling pathways by blocking the phosphorylation levels of p-ERK, p-S6, and p-STAT3. Bosutinib promotes autophagy.
  • Storage Instruction
    -80°C
  • UNSPSC
    51202000

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