BPA-B9

MedChem Express

BPA-B9

10

Research Use Only

C25H26N4O2

414.50

BPA-B9 is a RXRalpha ligand and antagonist targeting the pRXRalpha-PLK1 interaction. BPA-B9 has excellent RXRalpha-binding affinity (KD=39.29 +/- 1.12 nM). BPA-B9 inhibits the proliferation of cancer cells by inducing mitotic arrest and cell apoptosis[1].

O=C(NC1=NC=CC(C2=CC(N3CCC(CC3)CO)=NC=C2)=C1)/C=C/C4=CC=CC=C4

12131703