BPKDi [1201673-28-0]

MedChem Express

BPKDi [1201673-28-0]

10

1201673-28-0

Research Use Only

99.60

C21H28N6O

380.49

BPKDi is an inhibitor of PKD. BPKDi inhibits three members of the PKD family, PKD1, PKD2, and PKD3, with IC50 values of 1 nM, 9 nM, and 1 nM, respectively. BPKDi blocks signal-dependent phosphorylation and nuclear export of class IIa HDACs in cardiomyocytes and concomitantly suppresses hypertrophy of these cells[1].

O=C(N)C1=CC(C2=CC(NC3CCCCC3)=NC=C2)=NC(N4CCNCC4)=C1

2°C to 8°C

12352200