BPR1J-340 [1395051-72-5]
HY-116129
CAS Number1395051-72-5
Product group Chemicals
Molecular Weight542.63
Overview
- SupplierMedChem Express
- Product NameBPR1J-340 [1395051-72-5]
- Delivery Days Customer9
- CAS Number1395051-72-5
- CertificationResearch Use Only
- Molecular FormulaC29H34N8O3
- Molecular Weight542.63
- Scientific DescriptionBPR1J-340 is a potent FLT3 inhibitor with an IC50 of ~25 nM. BPR1J-340 inhibits the phosphorylation of FLT3 and STAT5 and triggered apoptosis in FLT3-ITD+ acute myeloid leukemia (AML) cells. BPR1J-340 exhibits significant anti-tumor activities[1].
- SMILESO=C(NC1=NNC(C2=CC=C(CNC(NC3=NOC(CC)=C3)=O)C=C2)=C1)C4=CC=C(CN5CCN(C)CC5)C=C4
- UNSPSC12352200