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CgoaEWY7Q-6EKH_aAAAAAA1Q4aY681.png

BR351 [960113-85-3]

Research Use Only
T10597
TargetMol Chemicals
CAS Number960113-85-3
DownloadMSDS
Product group Chemicals
Molecular Weight424.49
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Overview

  • Supplier
    TargetMol Chemicals
  • Product Name
    BR351 [960113-85-3]
  • Delivery Days Customer
    72
  • CAS Number
    960113-85-3
  • Category Supplier
    Chemical
  • Certification
    Research Use Only
  • Chemical Name
    BR351
  • Molecular Formula
    C20H25FN2O5S
  • Molecular Weight
    424.49
  • Scientific Description
    BR351 is a brain-penetrant MMP inhibitor with IC50 values of 4 nM for MMP2, 2 nM for MMP8, 11 nM for MMP9, and 50 nM for MMP13.
  • Shelf life instruction
    3 years
  • SMILES
    N([C@@H](C(NO)=O)C(C)C)(S(=O)(=O)C1=CC=C(OCCF)C=C1)CC2=CC=CC=C2
  • Storage Instruction
    -20°C
  • UNSPSC
    12352200

References

  • Wagner S, et al. Novel fluorinated derivatives of the broad-spectrum MMP inhibitors N-hydroxy-2(R)-[[(4-methoxyphenyl)sulfonyl](benzyl)- and (3-picolyl)-amino]-3-methyl-butanamide as potential tools for the molecular imaging of activated MMPs with PET. J Med Chem. 2007 Nov 15;50(23):5752-64.
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