BRAF Polyclonal Antibody

Reddot Biotech

BRAF Polyclonal Antibody

5

ImmunoHistoChemistry

Research Use Only

Polyclonal

0.74 mg/ml

Unconjugated

Braf

Braf transforming gene

9930012E13Rik; AA120551; AA387315; AA473386; Bra; B-raf; B-Raf proto-oncogene serine/threonine-protein kinase (p94); Braf2; Braf-2; C230098H17; C87398; D6Ertd631; D6Ertd631e; proto-oncogene B-Raf; serine/threonine-protein kinase B-raf

Rabbit

IgG

This gene encodes a protein belonging to the raf/mil family of serine/threonine protein kinases. This protein plays a role in regulating the MAP kinase/ERKs signaling pathway, which affects cell division, differentiation, and secretion. Mutations in this gene are associated with cardiofaciocutaneous syndrome, a disease characterized by heart defects, mental retardation and a distinctive facial appearance. Mutations in this gene have also been associated with various cancers, including non-Hodgkin lymphoma, colorectal cancer, malignant melanoma, thyroid carcinoma, non-small cell lung carcinoma, and adenocarcinoma of lung. A pseudogene, which is located on chromosome X, has been identified for this gene.

Mouse, Rat

-20°C

12352203