BRAF V600E/CRAF-IN-1 [2499499-56-6]

MedChem Express

BRAF V600E/CRAF-IN-1 [2499499-56-6]

10

2499499-56-6

Research Use Only

C25H17F6N3O2

505.41

BRAF V600E/CRAF-IN-1 (Compound 8b) is a potent inhibitor of BRAF V600E/CRAF. BRAF V600E/CRAF-IN-1 triggers apoptosis and cell cycle arrest at G0/G1 phase in HCT-116 colon cancer cell. BRAF V600E/CRAF-IN-1 has the potential for the research of cancer diseases[1].

COC1=C2C=CC(NC3=CC(NC(C4=CC(C(F)(F)F)=CC(C(F)(F)F)=C4)=O)=CC=C3)=NC2=CC=C1

12131703