Branebrutinib [1912445-55-6]

MedChem Express

Branebrutinib [1912445-55-6]

5

1912445-55-6

Research Use Only

99.78

C20H23FN4O2

370.42

Branebrutinib (BMS-986195) is a highly potent, selective covalent, irreversible inhibitor of Brutons tyrosine kinase (BTK), with an IC50 of 0.1 nM[1][2]. Branebrutinib is a click chemistry reagent, it contains an Alkyne group and can undergo copper-catalyzed azide-alkyne cycloaddition (CuAAc) with molecules containing Azide groups.

O=C(C1=CC(F)=C(N2C[C@@H](NC(C#CC)=O)CCC2)C3=C1NC(C)=C3C)N

-20°C,2°C to 8°C

12352200