
Western Blot Positive WB detected in: K562 whole cell lysate, Rat brain tissue All lanes: BRAP antibody at 7.5microg/ml Secondary Goat polyclonal to rabbit IgG at 1/50000 dilution Predicted band size: 68, 48 kDa Observed band size: 68 kDa
BRAP Antibody
CSB-PA773793LA01HU
ApplicationsImmunoFluorescence, Western Blot, ELISA, ImmunoHistoChemistry
Product group Antibodies
ReactivityHuman, Rat
TargetBRAP
Overview
- SupplierCusabio
- Product NameBRAP Antibody
- Delivery Days Customer20
- ApplicationsImmunoFluorescence, Western Blot, ELISA, ImmunoHistoChemistry
- CertificationResearch Use Only
- ClonalityPolyclonal
- ConjugateUnconjugated
- Gene ID8315
- Target nameBRAP
- Target descriptionBRCA1 associated protein
- Target synonymsBRAP2; BRCA1-associated protein; galectin-2-binding protein; IMP; impedes mitogenic signal propagation; renal carcinoma antigen NY-REN-63; RING finger protein 52; RING-type E3 ubiquitin transferase BRAP2; RNF52
- HostRabbit
- IsotypeIgG
- Protein IDQ7Z569
- Protein NameBRCA1-associated protein
- Scientific DescriptionNegatively regulates MAP kinase activation by limiting the formation of Raf/MEK complexes probably by inactivation of the KSR1 scaffold protein. Also acts as a Ras responsive E3 ubiquitin ligase that, on activation of Ras, is modified by auto-polyubiquitination resulting in the release of inhibition of Raf/MEK complex formation. May also act as a cytoplasmic retention protein with a role in regulating nuclear transport.
- ReactivityHuman, Rat
- Storage Instruction-20°C or -80°C
- UNSPSC41116161