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BRCC36, Human (His-SUMO)

Name: BRCC36, Human (His-SUMO)
SKU: HY-P72107_M09
Availability: BackOrder

HY-P72107

Protein IDP46736

Product group Proteins / Signaling Molecules

Overview

Supplier
MedChem Express
Product Name
BRCC36, Human (His-SUMO)
Delivery Days Customer
10
Certification
Research Use Only
Estimated Purity
90.00
Gene ID79184
Target name
BRCC3
Target description
BRCA1/BRCA2-containing complex subunit 3
Target synonyms
BRCC36, C6.1A, CXorf53, lys-63-specific deubiquitinase BRCC36, BRCA1-A complex subunit BRCC36, BRCA1/BRCA2-containing complex subunit 36, BRISC complex subunit BRCC36
Protein IDP46736
Protein Name
Lys-63-specific deubiquitinase BRCC36
Scientific Description
BRCC36 is a metalloprotease that selectively cleaves Lys-63 linked polyubiquitin chains, especially histones H2A and H2AX in the BRCA1-A complex during the DNA damage response. As the catalytic subunit of the BRISC complex, it also targets Lys-63-linked ubiquitin in various substrates, affecting mitotic spindle assembly and interferon signaling. BRCC36 Protein, Human (His-SUMO) is the recombinant human-derived BRCC36 protein, expressed by E. coli , with N-6*His, N-SUMO labeled tag.
Storage Instruction
-20°C
UNSPSC
41116100