BRD3308
M8594
CAS Number1550053-02-5
Product group Chemicals
Molecular Weight287.29
Overview
- SupplierAbMole BioScience
- Product NameBRD3308
- Delivery Days Customer9
- CAS Number1550053-02-5
- CertificationResearch Use Only
- Molecular FormulaC15H14FN3O2
- Molecular Weight287.29
- Scientific DescriptionBRD3308 is a highly selective HDAC3 inhibitor with an IC50 of 54 nM. BRD3308 is 23 times more selective to HDAC3 than HDAC1 (IC50:1.26 uM) or HDAC2 (IC50:1.34 uM). BRD3308 inhibits pancreatic bèta cell apoptosis induced by inflammatory cytokines or glucolipid toxic stress and increases functional insulin release. BRD3308 also activates HIV-1 transcription and disrupts HIV-1 latency.
- SMILESCC(=O)NC1=CC=C(C=C1)C(=O)NC2=CC=C(F)C=C2N
- UNSPSC12352200
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