BRD3308

Selleck Chemicals

BRD3308

9

Research Use Only

BRD3308 is a potant and highly selective inhibitor of HDAC3 with IC50 of 54 nM, 1.26 muM and 1.34 muM for HDAC3, HDAC1 and HDAC2, respectively. BRD3308 activates HIV-1 transcription. BRD3308 suppresses pancreatic bèta-cell apoptosis induced by inflammatory cytokines (glucolipotoxic stress) and increases functional insulin release.

12352200