The image on the left is immunohistochemistry of paraffin-embedded Human liver cancer tissue using CSB-PA047722(BRE Antibody) at dilution 1/40, on the right is treated with fusion protein. (Original magnification: x200)

BRE Antibody

Name: BRE Antibody
SKU: CSB-PA047722_C90
Availability: BackOrder

CSB-PA047722

ApplicationsWestern Blot, ELISA, ImmunoHistoChemistry

Product group Antibodies

TargetBABAM2

Overview

Supplier
Cusabio
Product Name
BRE Antibody
Delivery Days Customer
20
Applications
Western Blot, ELISA, ImmunoHistoChemistry
Certification
Research Use Only
Clonality
Polyclonal
Conjugate
Unconjugated
Gene ID9577
Target name
BABAM2
Target description
BRISC and BRCA1 A complex member 2
Target synonyms
brain and reproductive organ-expressed (TNFRSF1A modulator); brain and reproductive organ-expressed protein; BRCA1/BRCA2-containing complex subunit 45; BRCA1/BRCA2-containing complex, subunit 4; BRCA1-A complex subunit BRE; BRCC4; BRCC45; BRE; BRISC and BRCA1-A complex member 2
Host
Rabbit
Isotype
IgG
Protein IDQ9NXR7
Protein Name
BRISC and BRCA1-A complex member 2
Scientific Description
Brain and reproductive organ-expressed protein (BRE) is a 415 amino acid protein which binds to the intracellular juxtamembrane domain of the death receptor, tumor necrosis factor receptor 1 (TNF-R1). BRE also binds to the death receptor, FAS. BRE downregulates TNFa-induced activation of NFkB and may play a role in homeostasis or cellular differentiation in cells of epithelial, neural and germ line origins. It inhibits components of the death-inducing signaling complexes that are necessary for activation of the mitochondria, thereby mediating apoptosis. BRE is strongly expressed in the adrenal cortex, medulla, testis and pancreas, and is weakly expressed in the thymus, thyroid, stomach and small intestine.
Storage Instruction
-20°C or -80°C
UNSPSC
12352203

BRE Antibody

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Overview

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