Brepocitinib

MedChem Express

Brepocitinib [1883299-62-4]

5

1883299-62-4

Research Use Only

99.97

C18H21F2N7O

389.40

Brepocitinib (PF-06700841) is a potent dual Janus kinase 1 (JAK1) and TYK2 inhibitor with IC 50 s of 17 nM and 23 nM, respectively. Brepocitinib also inhibits JAK2 and JAK3 with IC 50 s of 77 nM and 6.49 microM, respectively [1] .

O=C([C@H]1C(F)(F)C1)N2C3CN(C4=NC(NC5=CN(C)N=C5)=NC=C4)CC2CC3

2°C to 8°C

12352200