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Chemical Structure
Chemical Structure
Chemical Structure

Brinzolamide [138890-62-7]

Research Use Only
CDX-B0424
Chemodex
CAS Number138890-62-7
Product group Chemicals
Estimated Purity>98%
Molecular Weight383.51
Price on request
Packing Size
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Overview

  • Supplier
    Chemodex
  • Product Name
    Brinzolamide [138890-62-7]
  • Delivery Days Customer
    10
  • CAS Number
    138890-62-7
  • Certification
    Research Use Only
  • Estimated Purity
    >98%
  • Molecular Formula
    C12H21N3O5S3
  • Molecular Weight
    383.51
  • Scientific Description
    Brinzolamide is a potent inhibitor of carbonic anhydrases (IC50=3.2nM and 45.3nM for CAII and CAIV, respectively) that lowers intraocular pressure by locally inhibiting carbonic anhydrase in the ciliary processes and suppressing aqueous humor secretion. Animal studies have found that one week of twice-daily topical ocular treatment with 2% brinzolamide significantly reduced IOP and enhanced optic nerve head blood flow. - Chemical. CAS: 138890-62-7. Formula: C12H21N3O5S3. MW: 383.51. Synthetic. Brinzolamide is a potent inhibitor of carbonic anhydrases (IC50=3.2nM and 45.3nM for CAII and CAIV, respectively) that lowers intraocular pressure by locally inhibiting carbonic anhydrase in the ciliary processes and suppressing aqueous humor secretion. Animal studies have found that one week of twice-daily topical ocular treatment with 2% brinzolamide significantly reduced IOP and enhanced optic nerve head blood flow.
  • SMILES
    O=S(C1=CC2=C(S1)S(N(CCCOC)C[C@@H]2NCC)(=O)=O)(N)=O
  • Storage Instruction
    -20°C
  • UNSPSC
    12352200