The image on the left is immunohistochemistry of paraffin-embedded Human thyroid cancer tissue using CSB-PA135237(BRK1 Antibody) at dilution 1/30, on the right is treated with synthetic peptide. (Original magnification: x200)
The image on the left is immunohistochemistry of paraffin-embedded Human thyroid cancer tissue using CSB-PA135237(BRK1 Antibody) at dilution 1/30, on the right is treated with synthetic peptide. (Original magnification: x200)
BRK1 Antibody
CSB-PA135237
ApplicationsELISA, ImmunoHistoChemistry
Product group Antibodies
ReactivityHuman, Mouse
TargetBRK1
Overview
- SupplierCusabio
- Product NameBRK1 Antibody
- Delivery Days Customer20
- ApplicationsELISA, ImmunoHistoChemistry
- CertificationResearch Use Only
- ClonalityPolyclonal
- ConjugateUnconjugated
- Gene ID55845
- Target nameBRK1
- Target descriptionBRICK1 subunit of SCAR/WAVE actin nucleating complex
- Target synonymsC3orf10, HSPC300, MDS027, hHBrk1, protein BRICK1, BRICK1, SCAR/WAVE actin nucleating complex subunit, haematopoietic stem/progenitor cell protein 300
- HostRabbit
- IsotypeIgG
- Protein IDQ8WUW1
- Protein NameProtein BRICK1
- Scientific DescriptionHSPC300 (hematopoietic stem cell protein 300) is also known as probable protein BRICK1 or C3orf10 (chromosome 3 open reading frame 10) and is a 75 amino acid protein that is expressed as two isoforms and localizes to both the cytoplasm and the cytoskeleton. HSPC300 is thought to regulate cytoskeletal organization and Actin polymerization. Free HSPC300 exists as homotrimers prior to its incorporation into the WAVE complex. The WAVE complex includes five proteins, one of which is HSPC300, that regulate the ARC (Arp2/3 complex) which is responsible for Actin nucleation and is Rac 1-dependent. Because HSPC300 is a highly conserved subunit of the WAVE complex across many species, it is thought to have the same or similar functions in many different organisms.
- ReactivityHuman, Mouse
- Storage Instruction-20°C or -80°C
- UNSPSC41116161
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