Bromo-PEG2-C2-azide [530151-56-5]

MedChem Express

Bromo-PEG2-C2-azide [530151-56-5]

10

530151-56-5

Research Use Only

98.70

C6H12BrN3O2

238.08

Bromo-PEG2-C2-azide is a non-cleavable ADC linker used in the synthesis of antibody-drug conjugates (ADCs). Bromo-PEG2-C2-azide is also a PEG-based PROTAC linker that can be used in the synthesis of PROTACs[1]. Bromo-PEG2-C2-azide is a click chemistry reagent, it contains an Azide group and can undergo copper-catalyzed azide-alkyne cycloaddition reaction (CuAAc) with molecules containing Alkyne groups. It can also undergo strain-promoted alkyne-azide cycloaddition (SPAAC) reactions with molecules containing DBCO or BCN groups.

BrCCOCCOCCN=[N+]=[N-]

-20°C

41115800