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Bruceantinol

M19040
AbMole BioScience
CAS Number53729-52-5
Product group Chemicals
Molecular Weight606.61
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Overview

  • Supplier
    AbMole BioScience
  • Product Name
    Bruceantinol
  • Delivery Days Customer
    9
  • CAS Number
    53729-52-5
  • Certification
    Research Use Only
  • Molecular Formula
    C30H38O13
  • Molecular Weight
    606.61
  • Scientific Description
    Bruceantinol is a STAT3 inhibitor demonstrating potent antitumor activity in in vitro and in vivo human colorectal cancer (CRC) models. Bruceantinol strongly inhibits STAT3 DNA-binding ability (IC50=2.4 pM), blocks the constitutive and IL-6-induced STAT3 activation, and suppresses transcription of MCL-1, PTTG1, survivin and c-Myc.
  • SMILES
    CC(C)(/C(/C)=C/C(O[C@H]([C@H]1[C@]([C@H]([C@@H]2O)O)(C(OC)=O)OC[C@@]1([C@@H](C1)O3)[C@H]2[C@@](C)(CC2=O)[C@@H]1C(C)=C2O)C3=O)=O)OC(C)=O
  • UNSPSC
    12352200

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