BRWD1 Antibody

Cusabio

BRWD1 Antibody

20

ELISA, ImmunoHistoChemistry

Research Use Only

Polyclonal

Unconjugated

BRWD1

bromodomain and WD repeat domain containing 1

C21orf107, CILD51, DCAF19, N143, WDR9, WRD9, bromodomain and WD repeat-containing protein 1, WD repeat protein WDR9-form2, WD repeat-containing protein 9, transcriptional unit N143

Rabbit

IgG

Bromodomain and WD repeat-containing protein 1

This gene encodes a member of the WD repeat protein family. WD repeats are minimally conserved regions of approximately 40 amino acids typically bracketed by gly-his and trp-asp (GH-WD) residues which may facilitate formation of heterotrimeric or multiprotein complexes. Members of this family are involved in a variety of cellular processes including cell cycle progression, signal transduction, apoptosis, and gene regulation. This protein contains 2 bromodomains and multiple WD repeats. This gene is located within the Down syndrome region-2 on chromosome 21. Alternative splicing of this gene generates multiple transcript variants encoding distinct isoforms. In mouse, this gene encodes a nuclear protein that has a polyglutamine-containing region that functions as a transcriptional activation domain which may regulate chromatin remodelling and associates with a component of the SWI/SNF chromatin remodelling complex.

Human, Mouse

-20°C or -80°C

41116161